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Nishal Mewasingh

Nishal Mewasingh

About

I have a BSc in Psychology (Brain & Cognition) from Erasmus University Rotterdam. During the final year of my bachelor’s, I gained research experience during an internship in the Department of Psychology & Psychiatry at St. Antonius Hospital Nieuwegein. Here, I worked on the preparation of a study focusing on the reduction of cardiac fear using behavioral experiments. This entailed the refinement of study materials (e.g., ensuring construct validity of questionnaires) and testing, refining and standardizing data exchange between electronic health records, raw data systems and statistical software. I collaborated with a team of psychologists, physiotherapists and data specialists. After completing my bachelor’s, my thesis was awarded with a co-authorship and I’m still involved in this research line at the intersection of cognitive psychology and neuroscience.

I am currently a Neuroscience MSc student at Erasmus Medical Center. In the Adams Lab, I work on two independent projects related to liquid biopsies in neurodegenerative disorders and the genetic architecture of skull shapes. On the one hand, I look at methylation patterns in cell-free DNA as a potential biomarker for Parkinson’s Disease. The goal is to work towards a diagnostic tool with the sensitivity and specificity to detect Parkinson-specific DNA fragments prior to current clinical diagnoses. On the other hand, I try to elucidate the genetic underpinnings of specific skull shapes measures by combining imaging and genetics data. Eventually, I strive to provide more genetic insights into the variety of skull shapes as seen by evolutionary pressure and interethnic differences. In both projects, I combine the mastery of contemporary skills with implementing new developments in the fields.

Finally, music is a great passion of mine. In my free time, I am a freelance musician and bandleader of a Latin band. Besides playing music, I am a proponent of non-pharmaceutical interventions in neurodegenerative disorders, such as music therapy in Parkinson’s Disease, and I would like to contribute to the efficacy of therapies in this field later in my career.

Positions

  • Master student Neuroscience, Erasmus MC, Rotterdam, the Netherlands

News

Oh what a year!
Oh what a year!
New grant awarded!
New grant awarded!
Review on genetic influences on hippocampal subfields published in Neurology Genetics
Review on genetic influences on hippocampal subfields published in Neurology Genetics
Hieab Adams wins Erasmus MC Fellowship!
Hieab Adams wins Erasmus MC Fellowship!
Cortical regions of interest GWAS published in Nature Communications
Cortical regions of interest GWAS published in Nature Communications
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Projects

Strategies for integrated analysis in Neurogenetic / Imaging Genetics studies

Strategies for integrated analysis in Neurogenetic / Imaging Genetics studies

Uncovering the genetic characterization of hippocampal subfields

Uncovering the genetic characterization of hippocampal subfields

Evaluating brain atrophy as an endophenotype for genetic studies of neurodegeneration

Evaluating brain atrophy as an endophenotype for genetic studies of neurodegeneration

Inheritance patterns of polygenic risk scores

Inheritance patterns of polygenic risk scores

Migraine genetic variants and their influence on cerebral blood flow

Migraine genetic variants and their influence on cerebral blood flow

Genetic correction of hippocampal volume in dementia prediction

Genetic correction of hippocampal volume in dementia prediction

Gene expression and its effects on the cerebral cortex

Gene expression and its effects on the cerebral cortex

Genetic factors predisposing to brain microbleeds

Genetic factors predisposing to brain microbleeds

Population-based induction of pluripotent stem cells

Population-based induction of pluripotent stem cells

Genome-wide association study of human head size

Genome-wide association study of human head size

Genetics of cognition and markers of neurodevelopment and neurodegeneration

Genetics of cognition and markers of neurodevelopment and neurodegeneration

Orbital telorism and neural correlates

Orbital telorism and neural correlates

Heritability and genome-wide association studies of orbital telorism

Heritability and genome-wide association studies of orbital telorism

Does polygenic burden for late-life neurodegeneration relate to early-life processes?

Does polygenic burden for late-life neurodegeneration relate to early-life processes?

Genetic scores for region-specific subcortical volume during adulthood generalize to infancy and early childhood

Genetic scores for region-specific subcortical volume during adulthood generalize to infancy and early childhood

qdecR: an R package for surface-wide analyses of FreeSurfer segmentations

qdecR: an R package for surface-wide analyses of FreeSurfer segmentations

Determinants of enrichment of genetic variant association- a genome wide association perspective

Determinants of enrichment of genetic variant association- a genome wide association perspective

High-dimensional imaging markers and neurodegenerative disorders: a pilot study

High-dimensional imaging markers and neurodegenerative disorders: a pilot study

Genetics of brain-derived neurotrophic factor: the CHARGE consortium

Genetics of brain-derived neurotrophic factor: the CHARGE consortium

Genetic architecture of subcortical brain structures

Genetic architecture of subcortical brain structures

Planar cell polarity pathway and development of the human visual cortex

Planar cell polarity pathway and development of the human visual cortex

Literature review of imaging research of neurodegeneration

Literature review of imaging research of neurodegeneration