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Polina Merbaum

Polina Merbaum

About

Hi, my name is Polina Merbaum. I have a background in medicine, particularly in neurology. After completing my MD degree and a two-year residency at the department of Algology and Peripheral Nervous System Diseases at Sechenov University, Moscow, Russian Federation, I have worked as a researcher. My field of interest was the prognosis of the outcome in patients with both Medication Overuse Headache and Migraine. During this study, I gained a wide clinical experience and analytical skills. To improve my ability in data analysis I took a Certificate Course in IBM Data Science Specialization.

Currently, I am enrolled in a Neuroscience Master Student Programme at Erasmus MC. In the Adams lab, I am working on the validation of cell-free DNA detection as a method in neurodegeneration research. With this project, our research group will establish biomarkers based on methylation patterns of cell-free DNA derived from various brain regions which might be used as evaluation tools in such disorders as Alzheimer’s disease, Parkinson’s disease, or frontotemporal dementia.

Since 2018 I am also a guest lecturer and a discussion club mentor at the University of Children, Moscow – an educational project that allows kids from 7 to 17 to have a closer look into science apart from formal education. I am convinced that only the one who can explain a complicated phenomenon to a child can truly understand it himself.

Positions

  • Master student Neuroscience, Erasmus MC, Rotterdam, the Netherlands

Publications

  • Merbaum PA, Tabeeva GR, Sergeev AV. Drug-induced headache: an analysis of therapeutic strategies. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2020;12(4):25–31. DOI: 10.14412/2074-2711-2020-4-25-31
  • Isaikin AI, Kavelina AV, Shor YuM, Merbaum PA et al. Sacroiliac joint dysfunction: clinical presentations, diagnosis, treatment. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, Neuropsychiatry, Psychosomatics. 2019;11(Suppl. 2):62-68 (In Russ.). DOI: 10.14412/2074-2711-2019-2S-62-68

News

Oh what a year!
Oh what a year!
New grant awarded!
New grant awarded!
Review on genetic influences on hippocampal subfields published in Neurology Genetics
Review on genetic influences on hippocampal subfields published in Neurology Genetics
Hieab Adams wins Erasmus MC Fellowship!
Hieab Adams wins Erasmus MC Fellowship!
Cortical regions of interest GWAS published in Nature Communications
Cortical regions of interest GWAS published in Nature Communications
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Projects

Strategies for integrated analysis in Neurogenetic / Imaging Genetics studies

Strategies for integrated analysis in Neurogenetic / Imaging Genetics studies

Uncovering the genetic characterization of hippocampal subfields

Uncovering the genetic characterization of hippocampal subfields

Evaluating brain atrophy as an endophenotype for genetic studies of neurodegeneration

Evaluating brain atrophy as an endophenotype for genetic studies of neurodegeneration

Inheritance patterns of polygenic risk scores

Inheritance patterns of polygenic risk scores

Migraine genetic variants and their influence on cerebral blood flow

Migraine genetic variants and their influence on cerebral blood flow

Genetic correction of hippocampal volume in dementia prediction

Genetic correction of hippocampal volume in dementia prediction

Gene expression and its effects on the cerebral cortex

Gene expression and its effects on the cerebral cortex

Genetic factors predisposing to brain microbleeds

Genetic factors predisposing to brain microbleeds

Population-based induction of pluripotent stem cells

Population-based induction of pluripotent stem cells

Genome-wide association study of human head size

Genome-wide association study of human head size

Genetics of cognition and markers of neurodevelopment and neurodegeneration

Genetics of cognition and markers of neurodevelopment and neurodegeneration

Orbital telorism and neural correlates

Orbital telorism and neural correlates

Heritability and genome-wide association studies of orbital telorism

Heritability and genome-wide association studies of orbital telorism

Does polygenic burden for late-life neurodegeneration relate to early-life processes?

Does polygenic burden for late-life neurodegeneration relate to early-life processes?

Genetic scores for region-specific subcortical volume during adulthood generalize to infancy and early childhood

Genetic scores for region-specific subcortical volume during adulthood generalize to infancy and early childhood

qdecR: an R package for surface-wide analyses of FreeSurfer segmentations

qdecR: an R package for surface-wide analyses of FreeSurfer segmentations

Determinants of enrichment of genetic variant association- a genome wide association perspective

Determinants of enrichment of genetic variant association- a genome wide association perspective

High-dimensional imaging markers and neurodegenerative disorders: a pilot study

High-dimensional imaging markers and neurodegenerative disorders: a pilot study

Genetics of brain-derived neurotrophic factor: the CHARGE consortium

Genetics of brain-derived neurotrophic factor: the CHARGE consortium

Genetic architecture of subcortical brain structures

Genetic architecture of subcortical brain structures

Planar cell polarity pathway and development of the human visual cortex

Planar cell polarity pathway and development of the human visual cortex

Literature review of imaging research of neurodegeneration

Literature review of imaging research of neurodegeneration